Cervical Cancer Diagnosis System using Convolutional Neural Network ResidualNet

Authors

  • Dian C. Rini Novitasari
  • Putri Wulandari
  • Dina Zatusiva Haq

DOI:

https://doi.org/10.47839/ijc.21.1.2518

Keywords:

cervical cancer, colposcopy, computer aided diagnosis system, deep learning, deep residual network

Abstract

Cervical cancer is a deadly disease attacking women. It represents 6.6% of all female cancers. The stadium of cervical cancer is determined based on the presence of carcinoma. The cervical cancer classification system can be used to help medical workers to analyze the stadium of cervical cancer. In this study, cervical cancer stages were divided into five classes, namely, normal cervix, stadium I, stadium II, stadium III, and stadium IV based on colposcopy images. The proposed method is one of deep learning methods, that is convolutional neural network (CNN) using deep residual network (ResidualNet) architecture. This study compared ResidualNet-18, ResidualNet-50, and ResidualNet-101 models and some conventional methods. The comparison results show that ResidualNet is more accurate than conventional methods. From the experiment, based on the accuracy value and elapsed time, ResidualNet-50 is worth using for cervical cancer classification. The result of this evaluation is higher than the maximum achievement of the ResidualNet-18 architecture. In addition, the elapsed time of the classification process using the ResidualNet-50 architecture with the accuracy, sensitivity, and specificity values reaching 100% is shorter than ResidualNet-101, which is 4397 s.

References

IARC, Latest Global Cancer Data, 2018.

D. C. R. Novitasari, A. Z. Foeady, M. Thohir, A. Z. Arifin, K. Niam, and A. H. Asyhar, “Automatic approach for cervical cancer detection based on Deep Belief Network (DBN) using colposcopy data,” Proceedings of the 2020 International Conference on Artificial Intelligence in Information and Communication (ICAIIC), 2020, pp. 415–420. https://doi.org/10.1109/ICAIIC48513.2020.9065196.

P. Autier and M. Boniol, “Mammography screening: A major issue in medicine,” Eur. J. Cancer, vol. 90, pp. 34–62, 2018. https://doi.org/10.1016/j.ejca.2017.11.002.

M. Masruroh, Cervical Cancer Classification Using Backpropagation Neural Network Model and image preprocessing with Spatial Operations (in Indonesia), Universitas Negeri Yogyakarta, 2016.

S. L. Bedell, L. S. Goldstein, A. R. Goldstein, and A. T. Goldstein, “Cervical cancer screening: past, present, and future,” Sex. Med. Rev., vol. 8, no. 1, pp. 28–37, 2020, doi: https://doi.org/10.1016/j.sxmr.2019.09.005.

A. Deverakonda and N. Gupta, “Diagnosis and treatment of cervical cancer: A review,” J Nurs Heal. Sci, vol. 2, no. 3, pp. 1–6, 2016.

Z. Yin et al., “Impact of sites versus number of metastases on survival of patients with organ metastasis from newly diagnosed cervical cancer,” Cancer Manag. Res., vol. 11, p. 7759, 2019. https://doi.org/10.2147/CMAR.S203037.

D. C. R. Novitasari, A. Lubab, A. Sawiji, and A. H. Asyhar, “Application of feature extraction for breast cancer using one order statistic, GLCM, GLRLM, and GLDM,” Adv. Sci. Technol. Eng. Syst. J., vol. 4, no. 4, pp. 115–120, 2019. https://doi.org/10.25046/aj040413.

W. Li et al., “Computer-aided Diagnosis (CAD) for cervical cancer screening and diagnosis: a new system design in medical image processing,” Proceedings of the International Workshop on Computer Vision for Biomedical Image Applications, 2005, pp. 240–250. https://doi.org/10.1007/11569541_25.

E. Hartenbach, “Colposcopy of the cervix, vagina, and vulva: A comprehensive textbook,” Journal of Lower Genital Tract Disease, vol. 8, no. 1, p. 86,2004. https://doi.org/10.1097/00128360-200401000-00018.

P. Basu, S. Joshi, and U. Poli, “Colposcopic Features of Cervical Intraepithelial Lesions,” in Preventive Oncology for the Gynecologist, Springer, 2019, pp. 145–157.

S. Gordon, G. Zimmerman, R. Long, S. Antani, J. Jeronimo, and H. Greenspan, “Content analysis of uterine cervix images: initial steps toward content based indexing and retrieval of cervigrams,” in Medical Imaging 2006: Image Processing, vol. 6144, p. 61444U, 2006. https://doi.org/10.1117/12.653025.

Q. Ji, J. Engel, and E. Craine, “Texture analysis for classification of cervix lesions,” IEEE Trans. Med. Imaging, vol. 19, no. 11, pp. 1144–1149, 2000. https://doi.org/10.1109/42.896790.

I. Claude, R. Winzenrieth, P. Pouletaut, and J.-C. Boulanger, “Contour features for colposcopic image classification by artificial neural networks,” Object Recognition Supported by User Interaction for Service Robots, 2002, vol. 1, pp. 771–774.

K. Tumer, N. Ramanujam, J. Ghosh, and R. Richards-Kortum, “Ensembles of radial basis function networks for spectroscopic detection of cervical precancer,” IEEE Trans. Biomed. Eng., vol. 45, no. 8, pp. 953–961, 1998. https://doi.org/10.1109/10.704864.

Vasudha, A. Mittal, and M. Juneja, “Cervix cancer classification using colposcopy images by deep learning method,” International Journal of Engineering Technology Science and Research (IJETSR), vol. 5, no. 3, pp. 426–432, 2018.

J. Ker, L. Wang, J. Rao, and T. Lim, “Deep learning applications in medical image analysis,” IEEE Access, vol. 6, pp. 9375–9389, 2017. https://doi.org/10.1109/ACCESS.2017.2788044.

B. Xu, N. Wang, T. Chen, and M. Li, “Empirical evaluation of rectified activations in convolutional network,” arXiv Prepr. arXiv1505.00853, 2015.

Y. Jiang, L. Chen, H. Zhang, and X. Xiao, “Breast cancer histopathological image classification using convolutional neural networks with small SE-ResidualNet module,” PLoS One, vol. 14, no. 3, p. e0214587, 2019. https://doi.org/10.1371/journal.pone.0214587.

T. J. Brinker et al., “Deep learning outperformed 136 of 157 dermatologists in a head-to-head dermoscopic melanoma image classification task,” Eur. J. Cancer, vol. 113, pp. 47–54, 2019.

S. Sasikala, M. Bharathi, and B. R. Sowmiya, “Lung cancer detection and classification using deep CNN,” International Journal of Innovative Technology and Exploring Engineering (IJITEE), vol. 8, no. 2, pp. 259–262, 2018.

K. Munir, H. Elahi, A. Ayub, F. Frezza, and A. Rizzi, “Cancer diagnosis using deep learning: A bibliographic review,” Cancers MDPI Journals, vol. 11, no. 1235, p. 1–36, 2019. https://doi.org/10.3390/cancers11091235.

K. He, X. Zhang, S. Ren, and J. Sun, “Deep residual learning for image recognition,” Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, 2016, pp. 770–778. https://doi.org/10.1109/CVPR.2016.90.

S. A. A. Ismael, A. Mohammed, and H. Hefny, “An enhanced deep learning approach for brain cancer MRI images classification using residual networks,” Artif. Intell. Med., vol. 102, p. 101779, 2020. https://doi.org/10.1016/j.artmed.2019.101779.

Y. Chen, Q. Zhang, Y. Wu, B. Liu, M. Wang, and Y. Lin, “Fine-tuning ResidualNet for breast cancer classification from mammography,” Proceedings of the International Conference on Healthcare Science and Engineering, 2018, pp. 83–96. https://doi.org/10.1007/978-981-13-6837-0_7.

L. A. Leonidas and Y. Jie, “Ship classification based on improved convolutional neural network architecture for intelligent transport systems,” Information, vol. 12, no. 8, p. 302, 2021, doi: https://doi.org/10.3390/info12080302.

C. Shorten and T. M. Khoshgoftaar, “A survey on image data augmentation for deep learning,” J. Big Data, vol. 6, no. 60, p. 7, 2019. https://doi.org/10.1186/s40537-019-0197-0.

A. Mikołajczyk and M. Grochowski, “Data augmentation for improving deep learning in image classification problem,” Proceedings of the 2018 International Interdisciplinary PhD Workshop (IIPhDW), 2018, pp. 117–122. https://doi.org/10.1109/IIPHDW.2018.8388338.

D. C. R. Novitasari et al., “Detection of covid-19 chest x-ray using support vector machine and convolutional neural network,” Commun. Math. Biol. Neurosci., vol. 2020, pp. 1-19, 2020.

S. Wan, Y. Liang, and Y. Zhang, “Deep convolutional neural networks for diabetic retinopathy detection by image classification,” Comput. Electr. Eng., vol. 72, pp. 274–282, 2018, doi: https://doi.org/10.1016/j.compeleceng.2018.07.042.

D. R. Nayak, R. Dash, and B. Majhi, “Classification of brain MR images using discrete wavelet transform and random forests,” Proceedings of the 2015 Fifth Natl. Conf. Comput. Vision, Pattern Recognition, Image Process. Graph., no. December, pp. 1–4, 2015. https://doi.org/10.1109/NCVPRIPG.2015.7490068.

E. C. Too, L. Yujian, S. Njuki, and L. Yingchun, “A comparative study of fine-tuning deep learning models for plant disease identification,” Comput. Electron. Agric., vol. 161, pp. 272–279, 2019. https://doi.org/10.1016/j.compag.2018.03.032.

Z. Zhong, M. Zheng, H. Mai, J. Zhao, and X. Liu, “Cancer image classification based on DenseNet model,” in Journal of Physics: Conference Series, 2020, vol. 1651, no. 1, p. 12143, doi: 10.1088/1742-6596/1651/1/012143.

X. Lei, H. Pan, and X. Huang, “A dilated CNN model for image classification,” IEEE Access, vol. 7, pp. 124087–124095, 2019. https://doi.org/10.1109/ACCESS.2019.2927169.

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Published

2022-03-30

How to Cite

Novitasari, D. C. R., Wulandari, P., & Haq, D. Z. (2022). Cervical Cancer Diagnosis System using Convolutional Neural Network ResidualNet. International Journal of Computing, 21(1), 61-68. https://doi.org/10.47839/ijc.21.1.2518

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Articles